For bones metastasis, I am taking the drug Boniva starting in April 2012 as part of the gammadelta therapy. It's a once monthly tablet but I think I did not follow the protocol fully when I took the drug. I am also considering taking the intravenous injection of Boniva instead for better absorption. Boniva is originally used to treat or prevent osteoporosis in women after menopause. The side effects of Boniva are
ent metastasis and also reduction in tumor, I am taking the drug cimetidine. Cimetidine is originally designed to treat ulcers of the stomach and intestines. Some of the common side effects include headache, dizziness, drowsiness, diarrhea and other less common effect includes mental/mood changes (e.g., agitation, confusion, depression, hallucinations), trouble urinating, stomach/abdominal pain, muscle/joint pain, breast swelling/soreness in males, decreased sexual ability (with very high doses of this medication). Long term taking of cimetidine can caused dementia. The following table shows the most common sites of cancer metastasis:
|Cancer type||Main sites of metastasis|
|Breast||Lungs, liver, bones|
|Colon||Liver, peritoneum, lungs|
|Kidney||Lungs, liver, bones|
|Lungs||Adrenal gland, liver, lungs|
|Melanoma||Lungs, skin/muscle, liver|
|Ovary||Peritoneum, liver, lungs|
|Pancreas||Liver, lungs, peritoneum|
|Prostate||Bones, lungs, liver|
|Rectum||Liver, lungs, adrenal gland|
|Stomach||Liver, peritoneum, lungs|
|Thyroid||Lungs, liver, bones|
|Uterus||Liver, lungs, peritoneum|
My next batch of drugs would be arriving from New York next week. The Cytoxan (cyclophospamide) which is part of the metronomic chemotherapy that I will be taking for lung and lymph node metastasis and also to prevent tumor growth. Nausea and vomiting commonly occur with cyclophosphamide therapy. Anorexia and, less frequently, abdominal discomfort or pain and diarrhea may occur.
As with any medicine, side effects are possible. However, not everyone who takes the medication will experience side effects. In fact, some people tolerate it quite well. When side effects do occur, in some cases, they are minor and either require no treatment or can easily be treated by the healthcare provider.
I think when I am already in such a poor health condition, I will just have to bear and manage the side effects for the good of the larger picture especially when they are not of life threatening in nature. My friend, Joanne from New Zealand asked me for Plan B. I don't have a plan B.